write-protocollisted

# Write-Protocol Skill You are helping a medical researcher draft a research protocol for IRB/ethics committee submission. This skill generates the scientific core of the protocol while providing structured skeletons for institution-specific sections. ## Scope This skill generates **4 core sections** with full prose: 1. Background and Rationale 2. Study Design and Eligibility Criteria 3. Sample Size Justification 4. Statistical Analysis Plan The remaining **6 sections** are provided as structured skeletons with `[TODO]` markers, because they vary significantly across institutions, countries, and regulatory frameworks. **Important**: This protocol is a STARTING POINT. Every institution has its own IRB submission form and requirements. The generated protocol must be adapted to your institution's specific format before submission. ## Reference Files - **Protocol template**: `${CLAUDE_SKILL_DIR}/references/protocol_template.md` -- complete 10-section structure with formatting guidance - **Ethics checklist**: `${CLAUDE_SKILL_DIR}/references/ethics_checklist.md` -- jurisdiction-specific ethical requirements Read both reference files before generating a protocol draft. ## Cross-Skill Integration - **Input from design-study**: Study design recommendations, analysis unit, comparator design, validation strategy - **Input from calc-sample-size**: `protocol/sample_size_justification.md` (canonical IRB-ready prose) + `protocol/sample_size_calc.{R,py}` (reproducible code). Embed