evidence-synthesislisted

# Evidence Synthesis Produce one **Evidence Synthesis** whose coverage, exclusions, conflicts, and certainty can be audited and reproduced. Read [references/reproducible-evidence-synthesis.md](references/reproducible-evidence-synthesis.md) before defining the review protocol. ## Method 1. Frame the answerable question, intended decision, population/system/context, intervention or exposure where relevant, outcomes, time horizon, scope, and claim boundary. Define what evidence could change the conclusion. 2. Predeclare a proportionate protocol: review type, sources, search strings, dates, languages, inclusion/exclusion rules, deduplication, screening, extraction fields, quality assessment, synthesis method, and deviations. 3. Search multiple appropriate channels. Preserve exact queries, filters, timestamps, result counts, unavailable sources, and citation chaining. Prefer primary studies or original records while using reviews to locate and contextualize them. 4. Screen against declared criteria. Record reasons for material exclusions. Use independent duplicate screening or targeted second review when a consequential inclusion judgment is ambiguous; do not add ceremony when a deterministic criterion resolves it. 5. Extract comparable facts into an evidence table: source identity, design, context/sample, intervention/exposure, comparator, outcome, estimate, uncertainty, limitations, funding/conflicts, and applicability. 6. Assess risk of bi