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search-encodelisted

Search and explore ENCODE Project genomics data. Use when the user wants to find experiments, files, or explore what data is available for specific assays, organs, cell lines, or targets.
ammawla/encode-toolkit · ★ 35 · AI & Automation · score 79
Install: claude install-skill ammawla/encode-toolkit
# Search ENCODE Data ## When to Use - User wants to find ENCODE experiments matching specific criteria (assay, organ, cell type, target) - User asks "what ENCODE data exists for [tissue/target/assay]?" - User wants to explore available data before downloading - User needs to find specific file types (BED, BAM, bigWig) across experiments - User wants to know how many experiments exist for a condition - User asks about available assays, organisms, or biosamples in ENCODE Help the user find ENCODE experiments and files. Use the appropriate tools based on what they need. ## Search Strategy 1. **Finding experiments**: Use `encode_search_experiments` with filters: - `assay_title`: "Histone ChIP-seq", "ATAC-seq", "RNA-seq", "TF ChIP-seq", "Hi-C", "CUT&RUN", "WGBS", etc. - `organ`: "pancreas", "brain", "liver", "heart", "kidney", "lung", etc. - `biosample_type`: "tissue", "cell line", "primary cell", "organoid" - `biosample_term_name`: specific name like "GM12878", "HepG2", "K562" - `target`: ChIP/CUT&RUN target like "H3K27me3", "H3K4me3", "CTCF", "p300" - `organism`: "Homo sapiens" (default) or "Mus musculus" 2. **Finding files across experiments**: Use `encode_search_files` when the user wants specific file types from multiple experiments. 3. **Exploring available data**: Use `encode_get_facets` to see counts of what exists before searching. Use `encode_get_metadata` to list valid filter values. 4. **Getting experiment details**: Use `encode_get_experiment