bio-logiclisted

# Bio-Logic: Scientific Reasoning Evaluation Use structured frameworks to evaluate scientific claims, methodology, and evidence strength. ## Instructions 1. Identify the task (claim assessment, paper critique, study design review, project interpretation, or hypothesis revision). 2. For project work, maintain a hypothesis register with at least 5 distinct active hypotheses until the project is no longer exploratory. 3. After each major intermediate result, reflect on what changed, revise hypothesis status, and identify the next discriminating check. 4. When findings need context, pair this reasoning with a literature-search skill such as `/polars-dovmed`, then revise hypotheses against the literature. 5. Apply the relevant checklist below. 6. Structure output using the provided format. ### Project Hypothesis Loop Use this loop for omics projects, unexpected results, exploratory analyses, and any request that asks what results mean. 1. **Initialize**: create at least 5 working hypotheses. Include biological mechanisms, technical artifacts, null explanations, sampling/batch effects, and annotation/database artifacts where relevant. 2. **Build an analysis playbook**: search the literature for the inferred organism, virus group, data type, or closest lineage. Summarize typical analyses, comparison baselines, markers/features, plots, and outlier criteria used by scientists in that literature. 3. **Reflect**: for every major intermediate result or QC gate, state the observatio