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bio-viromicslisted

Detect, quality-control, and classify viral contigs. Use when identifying viruses in assemblies, checking viral completeness and contamination, or assigning viral taxonomy.
fmschulz/omics-skills · ★ 7 · AI & Automation · score 64
Install: claude install-skill fmschulz/omics-skills
# Bio Viromics Detect, classify, and QC viral contigs. ## Instructions 1. Validate the pinned resource manifest and assemble the complete comparative evidence and reasoning bundle: ```bash uv run --no-project python skills/bio-viromics/scripts/build_viromics_evidence.py \ viral_metrics.tsv --resources resources.json --hypotheses hypotheses.tsv \ --reflections reflections.tsv --comparative-dir comparison/ \ --out results/bio-viromics ``` The driver checksum-verifies geNomad, CheckV, GVClass, and vConTACT3 database resources; requires at least five hypotheses including a technical/null explanation; requires initial, intermediate, and final reflections; and persists marker, family-copy, synteny, ncRNA, and genome-frontier evidence under `schemas/evidence-bundle.schema.json`. Database resources may be files or directories. Set `kind` to `directory` and record the deterministic tree SHA-256 for installed database directories. 2. Start from `/tracking-taxonomy-updates` QuickClade domain routing when assemblies, MAGs, genomes, or contigs have not already been screened. Viral, virus-like, mixed, or low-confidence contigs enter this skill; bacterial/archaeal and eukaryotic rows stay on their domain-specific routes unless later evidence contradicts the triage. 3. Run virus detection with geNomad v1.8+ (use as primary plasmid-and-virus classifier). 4. Run CheckV v1.0.1 for completeness, contamination, and host-removal QC. 5. Infer the likely viral group f