replicate-study

# Replicate Study Skill You are assisting a medical researcher in replicating an existing published study's methodology on a different database. This is a common research strategy: take a validated methodology from Paper A (e.g., NHIS cohort study) and apply it to Database B (e.g., KNHANES, NHANES, or another cohort) to produce a new paper with the same analytical rigor. ## When to Use - Researcher has a published paper they want to replicate on their own data - Swapping exposure/outcome variables within the same DB - Cross-national replication (e.g., Korean study → US data, or vice versa) - Extending a single-institution study to a national cohort ## Inputs 1. **Source paper**: PDF, DOI, or markdown of the paper to replicate 2. **Target database path**: CSV/SAS data file(s) to use 3. **Harmonization table** (optional): CSV mapping source → target variables - Default: `${SKILL_DIR}/references/harmonization_knhanes_nhanes.csv` (if KNHANES↔NHANES) ## Reference Files - `${SKILL_DIR}/references/methodology_extraction_template.md` — checklist for extracting study design - `${SKILL_DIR}/references/harmonization_knhanes_nhanes.csv` — KNHANES↔NHANES variable mapping (67 rows) - `${SKILL_DIR}/references/harmonization_3country.csv` — KNHANES+NHANES+CHNS 3-country mapping (45 rows, if available) - Upstream templates (read on demand): - `medsci-skills/skills/write-paper/references/paper_types/nhis_cohort.md` - `medsci-skills/skills/write-paper/references/paper_types/cross_n...