folklore-variant-evidence

# Folklore Variant Evidence Use Folklore Clinical Variant Interpretation MCP to retrieve structured public variant evidence, automated variant-level ACMG/AMP decision support, provenance, and source-linked literature for professional review. Keep the workflow limited to public identifiers and preserve every explicit outcome state. Adapter 1.5.0 also provides ClinGen Gene-Disease Validity assertions; source coverage is bounded, not every known association. Folklore Clinical Variant Interpretation MCP is published by Helena Bioinformatics. Its hosted endpoint is: ```text https://api.helena.bio/folklore/v1/mcp ``` No account or API key is required. The public Apache-2.0 adapter and contract are available at <https://github.com/helena-bioinformatics/folklore-mcp>. ## Minimal connection example A host without native MCP support can make the same public JSON-RPC call: ```bash curl --silent --show-error --fail-with-body --max-time 60 \ -X POST https://api.helena.bio/folklore/v1/mcp \ -H 'Content-Type: application/json' \ -H 'Accept: application/json, text/event-stream' \ -H 'MCP-Protocol-Version: 2026-07-28' \ -H 'Mcp-Method: tools/call' \ -H 'Mcp-Name: search_variant_evidence' \ -d '{"jsonrpc":"2.0","id":1,"method":"tools/call","params":{"_meta":{"io.modelcontextprotocol/protocolVersion":"2026-07-28","io.modelcontextprotocol/clientCapabilities":{}},"name":"search_variant_evidence","arguments":{"assembly":"GRCh38","query":"rs80357914"}}}' ``` Inspect the return...