genomic-intelligence
FeaturedPredict regulatory features, gene structure, and expression directly from DNA sequence using Genomic Intelligence's hosted transformer DNA language models — no local GPU or model weights. Six tasks over a REST API and a hosted MCP server (keyless public demo): promoter regions, splice donor/acceptor sites, enhancer activity, chromatin state, sequence-to-expression (log TPM), and de-novo gene annotation, plus a composite find-genes-then-predict-expression workflow. Use when the user has a gene symbol, a genomic region, or a DNA/FASTA sequence and wants any of these predictions, mentions Genomic Intelligence, genomicintelligence.ai, api.genomicintelligence.ai, or mcp.genomicintelligence.ai.
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Quality Score: 99/100
Skill Content
Details
- Author
- K-Dense-AI
- Repository
- K-Dense-AI/scientific-agent-skills
- Created
- 11 months ago
- Last Updated
- 5 days ago
- Language
- Python
- License
- MIT
Integrates with
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genomic-prediction
Execution blueprints and code templates for fitting genomic prediction models, including GBLUP, GFBLUP, MultiBLUP, Bayesian methods, and Random Forest using peer-reviewed software. Strictly incorporates robust self-auditing, high-clarity code commenting, big data performance safeguards, and strict matrix alignment rules.
alphagenome
Look up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq, DNase, ATAC, ChIP-TF, ChIP-histone, CAGE, PRO-cap, splicing, polyadenylation and contact-map tracks), score variants or scan windows on demand with the AlphaGenome model for human and mouse (variant scoring, in silico mutagenesis, REF-versus-ALT track prediction), and build Atlas website deep links. Use when the user mentions AlphaGenome, AlphaGenome Atlas, AVI or AlphaGenome Variant Impact, DeepMind variant effect prediction, or wants to prioritise or mechanistically interpret non-coding, regulatory, splicing, enhancer, promoter, or chromatin-accessibility effects of SNVs from a VCF, credible set, or region. Research use only; not a clinical tool.
genomics-precision-medicine
When the user wants to design, build, or integrate genomics and precision-medicine informatics. Use when the user mentions "genomics," "precision medicine," "VCF," "gVCF," "BAM," "CRAM," "FASTQ," "variant calling," "variant annotation," "HGVS," "ACMG," "AMP/CAP/ASCO," "ClinGen," "ClinVar," "PharmGKB," "CPIC," "pharmacogenomics," "PGx," "GA4GH," "VRS," "Phenopackets," "FHIR Genomics," "mCODE," "molecular tumor board," "liquid biopsy," "ctDNA," "MRD," "polygenic risk score," "PRS," "incidental findings," "ACMG SF," "GINA," "GRCh38," or "T2T-CHM13." For broader clinical AI lifecycle, see clinical-ai-ml. For SaMD on genomic algorithms, see fda-samd. For the EHR integration of orders/results, see ehr-integration and fhir-integration.