fusion-gene-detector

# Fusion Gene Detector Skill ## Purpose Enable gene fusion detection for oncology applications with multiple caller integration. ## Capabilities - RNA-based fusion calling - DNA-based fusion detection - Multi-caller consensus - Visualization of fusion events - Known fusion annotation - Clinical actionability assessment ## Usage Guidelines - Use multiple callers for sensitivity - Build consensus from different algorithms - Annotate with known fusion databases - Visualize fusion breakpoints - Assess clinical actionability - Document caller combinations ## Dependencies - STAR-Fusion - Arriba - FusionCatcher ## Process Integration - Tumor Molecular Profiling (tumor-molecular-profiling) - RNA-seq Differential Expression Analysis (rnaseq-differential-expression)