ct-status-diff

> Methodology inspired by publicly taught clinical-trial monitoring frameworks; all text is an original paraphrase. ## Defaults | Parameter | Default Value | Rationale | |-----------|---------------|-----------| | window | latest two snapshots | The diff is always between consecutive stored states | | categories | all 11 | Complete change report; filter on request | | risk_flags | on | Terminated / Downsized are surfaced first | | gap_statement | on | Missing snapshot weeks are stated, never inferred | ## Preflight Run canonical pre-flight per `contracts/preflight.md`. Include the `X-Agentii-Trace` header on every tool call per `contracts/x-agentii-trace-header.md` — carry the `_run_id` from your first tool result and name yourself (and your parent, if you were spawned). Confirm the snapshot coverage via `get_ct_status_changes` before framing any readout. ## Triggers - "What changed on clinicaltrials.gov for my coverage this week?" - "Which of [ticker]'s trials moved this week?" - "Any trial delays or accelerations in my watchlist?" - "Flag every terminated or downsized trial since last week." - "Did any recruitment complete for [ticker]?" - "Show the previous and new primary-completion dates for [drug]'s program." - "Which trials were upsized this week?" - "Is [trial]'s enrollment collapsing?" - "Summarize the week's trial-registry changes for the sector." - "What should I re-check ahead of [readout] based on registry moves?" - "Compare this week's diff to the month-ag...